Antibody Engineering

We offer a comprehensive range of recombinant antibody services, including custom antigen discovery, antibody re-engineering and bespoke bio-conjugation.

At Virax Biolabs, we specialize in delivering customized antibody development and production solutions tailored to your research needs. Our technical team will work closely with you to create a personalized plan. Are you working on novel targets? Do you need reliable and cheaper alternatives to catalogue antibodies? Don’t hesitate to talk to us.
 
Virax Biolabs services cover every step, from antigen design and expression, to production, screening, and characterization, making us the ideal partner for anyone looking for cost-effective solutions.

As your dedicated partner in research, we prioritize specificity, antigenicity, and structural integrity in every project, conducting thorough bioinformatic analyses to optimize binding effectiveness. Whether you require full-service antibody development or specific aspects of our expertise, our UK team ensures convenient, local support.

Our comprehensive range of services includes:

Protein sequencing
Antigen discovery
Antigen re-engineering
Custom conjugation
Screening assays
Production
Purification

All supported by advanced analytical techniques

Antibody Development

We provide specialised Phage Display Services to accelerate the discovery of antibodies, identifying high-affinity binders with precision, targeting specific antigens for a wide range of research applications. Our streamlined monoclonal antibody development services ensure efficient and reliable results in as little as 2 months, addressing common challenges like immunogenicity and humanization.

Workflow

  • Target Antigen Validation: we verify the target antigen and can also produce recombinant antigens if needed.
  • Biopanning: selection of high-affinity antibodies through multiple rounds of library screening.
  • Biochemical Validation and Sequencing: we screen hit molecules to confirm antibody binding, kinetics and sequence.
  • Optional reformatting: We offer a range of antibody formatting services.
  • Antibody production: via one of our in-house expression systems.

End-to-End Support

Robust Quality Control

Competitive Prices

Fast Turnaround

Scalable Production

Diverse Antibody Formats

Antibody Formatting

We offer a range of antibody formatting services, including:

  • Affinity maturation
  • Antibody humanisation
  • Creation of bi-specific antibodies
  • IgG conversion
  • Site-directed mutagenesis
  • Bio-conjugation

Formatting can be performed on novel antibodies as well as antibodies already in use in your lab.

Antibody Expression

We have a number of expression platforms, including both mammalian and bacterial expression systems. All antibodies are then purified, analytical and preparative size exclusion chromatography (SEC) performed and full quality control analysis undertaken.

Antibody Sequency

Antibody Sequency

Antibody Sequency

Antibody Sequency

Antibody Sequency

Antibody Sequency

Mammalian Expression
Bacterial Expression

HEK Cells

Easy to Manupulate and transiently transfect
Grow rapidly
Generate human glycosylation patterns

CHO Cells​

Produce high yields of recombinant proteins
Generate human-compatible glycosylation patterns
Easy to scale up for manufacturing

E. coli​

Lower cost
Grow extremely quickly
Easy to scale up for manufacturing

We put you in control with flexible, customizable options that allow you to steer your project in the direction you need, and our experienced specialists will work closely with you to create a personalized plan, ensuring your project’s success.

Get in touch to discuss your antibody needs

Contact us to discover how we can help you find the custom antibody solution that’s right for you.

Have Questions? Check our FAQ page

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