£ 150.00
As a proinflammatory cytokine, IFN-γ plays a significant role in activating macrophages and endothelial cells, enhancing their pathogen-killing capabilities. It regulates immune responses by modulating the activity of antigen-presenting cells and T cells. IFN-γ is critical for both innate and adaptive immunity against viral, bacterial, and protozoal infections due to its ability to inhibit viral replication directly and through its immunostimulatory and immunomodulatory effects. One of its key functions is the induction of MHC class II molecule expression, which improves antigen presentation and immune recognition.
The Human IFN-γ Enzyme-Linked ImmunoSpot (ELISpot) assay is a sensitive immunological technique that detects cytokine secretion at the single-cell level. Unlike methods such as ELISA or RT-PCR, which measure cytokine or cytokine-related signals at the population level, ELISpot enables identification and quantification of the frequency of individual cytokine-secreting cells. In the context of IFN-γ analysis, the assay can therefore be used to assess cellular immune responses by determining the frequency of stimulated effector cells that secrete IFN-γ.
Pre-coated kits are ready-to-use, helping labs save time and reduce human touchpoints during setup, ideal for accelerating research workflows.
As a proinflammatory cytokine, IFN-γ plays a significant role in activating macrophages and endothelial cells, enhancing their pathogen-killing capabilities. It regulates immune responses by modulating the activity of antigen-presenting cells and T cells. IFN-γ is critical for both innate and adaptive immunity against viral, bacterial, and protozoal infections due to its ability to inhibit viral replication directly and through its immunostimulatory and immunomodulatory effects. One of its key functions is the induction of MHC class II molecule expression, which improves antigen presentation and immune recognition.
The Human IFN-γ Enzyme-Linked ImmunoSpot (ELISpot) assay is a sensitive immunological technique that detects cytokine secretion at the single-cell level. Unlike methods such as ELISA or RT-PCR, which measure cytokine or cytokine-related signals at the population level, ELISpot enables identification and quantification of the frequency of individual cytokine-secreting cells. In the context of IFN-γ analysis, the assay can therefore be used to assess cellular immune responses by determining the frequency of stimulated effector cells that secrete IFN-γ.
Pre-coated kits are ready-to-use, helping labs save time and reduce human touchpoints during setup, ideal for accelerating research workflows.
Virax Biolabs develops and provides immunology-profiling solutions, with a focus on T cell diagnostics and immune monitoring. Their offerings include research-use products (e.g., peptide pools, ELISpot/FluoroSpot kits, high-affinity antibodies) as well as custom immunology services (such as recombinant antibody engineering, peptide synthesis and protein sequencing).
Virax Biolabs offers a comprehensive range of products to support immunology research and diagnostic development. Their primary product categories include pathogen-specific peptide pools that enable T cell stimulation and immune-response analysis, ELISpot and FluoroSpot kits designed for measuring cytokine secretion and other immune markers, and high-affinity antibodies suitable for use in assays such as ELISA, flow cytometry, and ELISpot. Together, these products provide researchers with precise tools for profiling immune responses in various disease and vaccine studies.
Virax Biolabs provides a range of custom immunology services to meet the diverse needs of academic and industry clients. These services include recombinant antibody engineering, which involves antigen discovery, sequencing, formatting, and bio-conjugation. They also offer custom peptide synthesis and protein sequencing using advanced mass spectrometry, as well as laboratory services that support ELISA, ELISpot, FluoroSpot, and flow cytometry assays. These custom services are designed to help researchers accelerate discovery and optimize immune-response studies.
Virax Biolabs primarily serves researchers and organizations engaged in immunology, infectious disease, and vaccine development. Their customer base includes academic laboratories, biotechnology companies, and pharmaceutical firms that require high-quality immune-profiling tools and diagnostic support. By providing both off-the-shelf research products and tailored immunology services, Virax Biolabs enables scientists to investigate T cell activity, evaluate vaccine efficacy, and develop new diagnostic platforms.
Virax Biolabs’ headquarters is located at BioCity Glasgow, Bo’Ness Road, Newhouse, Lanarkshire, ML1 5UH, United Kingdom. Inquiries can be made through the “Contact” section of their website at viraxbiolabs.com.
Many of Virax Biolabs’ products, including peptide pools and ELISpot kits, are intended for research use in immune-profiling and in-vitro studies. However, the company is also developing in-vitro diagnostic (IVD) platforms and T cell diagnostics for applications such as chronic inflammation and immune exhaustion. The intended use and regulatory status vary by product, so customers should refer to the specific product details or contact the company directly for clarification.
