ELISpot Human IFN-γ Kit + Lyme Disease Peptide Pool
Cat #:
3038

ELISpot Human IFN-γ Kit + Lyme Disease Peptide Pool

£ 280.00

Shipped within 2-3 days
Product Details
Application: ELISpot
Analyte: IFN-γ
Reactivity: Human
Storage: Store plates and reagents between 2 and 8°C. Peptide pool vial must be stored at -20 °C or below.
Shelf Life: 12 months
Peptide Pools​: ImmuneSelect Lyme Disease (41 peptides from Borrelia burgdorferi)
Plates​: ELISpot plate precoated with IFN-γ capture antibody
Detection mAb​​: Biotinylated recombinant IFN-γ antibody
Enzyme conjugate​: Streptavidin-ALP (Alkaline Phosphatase)
Substrate: BCIP/NBT Ready-to-use solution
Blocking agent: Bovine Serum Albumin (BSA)
Lyme disease, caused by the bacterium Borrelia burgdorferi, is the most common vector-borne illness in North America and Europe. Transmitted by the bite of infected ticks, Lyme disease can lead to a wide range of clinical manifestations, including erythema migrans (a characteristic skin rash), arthritis, carditis, and neurological symptoms such as meningitis and facial palsy. Early diagnosis is critical to prevent the progression to more severe, disseminated forms of the disease, which can result in long-term health complications, increased healthcare costs, and significant morbidity. Diagnosis and prompt antibiotic treatment initiated in the early stages of Lyme disease typically leads to a full recovery, whereas delayed diagnosis and treatment are associated with chronic symptoms and more complex management.

The Lyme Disease Human IFN-γ Enzyme-Linked ImmunoSpot (ELISpot) kit is a highly sensitive method used to detect and quantify individual cells that secrete IFN-γ after stimulation with the ImmuneSelect Lyme Disease Peptide Pool. This assay is utilized to monitor cellular immune responses at the single-cell level and reliably detects and measures human IFN-γ secretion by Lyme Disease stimulated effector cells.

 

Description

Lyme disease, caused by the bacterium Borrelia burgdorferi, is the most common vector-borne illness in North America and Europe. Transmitted by the bite of infected ticks, Lyme disease can lead to a wide range of clinical manifestations, including erythema migrans (a characteristic skin rash), arthritis, carditis, and neurological symptoms such as meningitis and facial palsy. Early diagnosis is critical to prevent the progression to more severe, disseminated forms of the disease, which can result in long-term health complications, increased healthcare costs, and significant morbidity. Diagnosis and prompt antibiotic treatment initiated in the early stages of Lyme disease typically leads to a full recovery, whereas delayed diagnosis and treatment are associated with chronic symptoms and more complex management.

Application

The Lyme Disease Human IFN-γ Enzyme-Linked ImmunoSpot (ELISpot) kit is a highly sensitive method used to detect and quantify individual cells that secrete IFN-γ after stimulation with the ImmuneSelect Lyme Disease Peptide Pool. This assay is utilized to monitor cellular immune responses at the single-cell level and reliably detects and measures human IFN-γ secretion by Lyme Disease stimulated effector cells.

 

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Frequently Asked Questions

Virax Biolabs develops and provides immunology-profiling solutions, with a focus on T cell diagnostics and immune monitoring. Their offerings include research-use products (e.g., peptide pools, ELISpot/FluoroSpot kits, high-affinity antibodies) as well as custom immunology services (such as recombinant antibody engineering, peptide synthesis and protein sequencing).

Virax Biolabs offers a comprehensive range of products to support immunology research and diagnostic development. Their primary product categories include pathogen-specific peptide pools that enable T cell stimulation and immune-response analysis, ELISpot and FluoroSpot kits designed for measuring cytokine secretion and other immune markers, and high-affinity antibodies suitable for use in assays such as ELISA, flow cytometry, and ELISpot. Together, these products provide researchers with precise tools for profiling immune responses in various disease and vaccine studies.

Virax Biolabs provides a range of custom immunology services to meet the diverse needs of academic and industry clients. These services include recombinant antibody engineering, which involves antigen discovery, sequencing, formatting, and bio-conjugation. They also offer custom peptide synthesis and protein sequencing using advanced mass spectrometry, as well as laboratory services that support ELISA, ELISpot, FluoroSpot, and flow cytometry assays. These custom services are designed to help researchers accelerate discovery and optimize immune-response studies.

Virax Biolabs primarily serves researchers and organizations engaged in immunology, infectious disease, and vaccine development. Their customer base includes academic laboratories, biotechnology companies, and pharmaceutical firms that require high-quality immune-profiling tools and diagnostic support. By providing both off-the-shelf research products and tailored immunology services, Virax Biolabs enables scientists to investigate T cell activity, evaluate vaccine efficacy, and develop new diagnostic platforms.

Virax Biolabs’ headquarters is located at BioCity Glasgow, Bo’Ness Road, Newhouse, Lanarkshire, ML1 5UH, United Kingdom. Inquiries can be made through the “Contact” section of their website at viraxbiolabs.com.

Many of Virax Biolabs’ products, including peptide pools and ELISpot kits, are intended for research use in immune-profiling and in-vitro studies. However, the company is also developing in-vitro diagnostic (IVD) platforms and T cell diagnostics for applications such as chronic inflammation and immune exhaustion. The intended use and regulatory status vary by product, so customers should refer to the specific product details or contact the company directly for clarification.

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